Supplements

Compounds & Therapies

ALCAR / L-Carnitine: A Practical Guide

Alpha-Ketoglutarate (AKG)

A metabolic intermediate supporting cellular energy production and muscle protein synthesis

Alpha-Lipoic Acid: A Practical Guide

Apigenin

Chamomile-derived flavonoid with CD38 inhibition and NAD+ modulation potential

Astaxanthin

A powerful carotenoid antioxidant supporting eye health, athletic recovery, and cardiovascular function

Berberine

A plant alkaloid with emerging evidence for metabolic and cardiovascular support, requiring clinical context

Boron

An essential trace mineral supporting bone health, hormonal balance, and cognitive function

Citrulline (L-Citrulline)

Amino acid nitric oxide precursor for vascular function and athletic performance

Collagen

Hydrolyzed peptides supporting skin, joint, and connective tissue health through targeted amino acid delivery

Curcumin & Turmeric Extract

A powerful polyphenol supporting inflammatory control and antioxidant defense, with bioavailability optimization required

DIM (Diindolylmethane)

Cruciferous phytochemical for estrogen metabolism support and hormonal balance

Fadogia Agrestis

A traditional West African plant with limited regulatory guidance and concerning preclinical safety signals requiring clinical oversight

Fisetin

Strawberry-derived flavonoid senolytic with Mayo Clinic clinical trial support

Glucosamine and Chondroitin — The Honest 2026 Read

Glucosamine and chondroitin sulfate are naturally occurring compounds found in healthy cartilage. Glucosamine is an amino sugar used by the body in glycosaminoglycan and proteoglycan synthesis; chondroitin sulfate is a long-chain sulfated…

HMB (Beta-Hydroxy Beta-Methylbutyrate)

A leucine metabolite supporting muscle protein synthesis and exercise recovery with solid clinical evidence

Inulin

A prebiotic fiber supporting gut microbiota, digestive health, and metabolic markers

L-Carnitine Tartrate (LCLT)

Lactoferrin

Leucine

An essential branched-chain amino acid crucial for muscle protein synthesis and metabolic signaling

Lovaza and Vascepa: How the Two Prescription Omega-3s Differ from Each Other and from OTC Fish Oil and Krill Oil

Two prescription omega-3s are commonly confused. Lovaza (EPA+DHA) treats severe hypertriglyceridemia; Vascepa (pure EPA) is the only one with cardiovascular outcomes evidence. Plus: where OTC fish oil and krill oil fit, and the dose-dependent atrial fibrillation signal.

Lysine

An essential amino acid supporting collagen synthesis, immune function, and herpes simplex virus management

Macular Protection Stack (AREDS2)

The Age-Related Eye Disease Study (AREDS) and its successor AREDS2 are among the most rigorously conducted nutritional intervention trials in modern medicine. Funded by the National Eye Institute and conducted over more than two decades, the trials…

NAC (N-Acetyl Cysteine)

Cellular antioxidant and glutathione precursor for robust defense

NAD+ Precursors (NMN/NR)

Cellular energy currency and sirtuin activator with evolving regulatory status

Nattokinase — Fibrinolytic Enzyme Supplement

Nattokinase is a serine protease enzyme extracted from natto, the traditional Japanese fermented soybean food. It was discovered and characterized by Sumi and colleagues in 1987 as the active fibrinolytic constituent in natto, with strong in vitro…

Neprinol

Proprietary systemic enzyme blend for proteolytic and fibrinolytic support

Pentadecanoic Acid (C15:0)

Odd-chain saturated fatty acid for metabolic flexibility and cellular signaling

Pharmaceutical-Grade GABA

γ-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the mammalian central nervous system. Oral GABA supplements have been marketed for decades for stress, anxiety, sleep, and general relaxation. The classical neuroscience…

Phosphatidylserine: A Practical Guide

Polygala Tenuifolia

Polygala tenuifolia (Chinese name: yuan zhi, 远志) is a perennial herb whose root has been used in traditional Chinese medicine for over two thousand years. Classical TCM indications focused on insomnia, restlessness, palpitations, cognitive…

Pterostilbene

Methylated resveratrol analog with superior bioavailability and sirtuin activation

Quercetin

Bioflavonoid antioxidant and senolytic candidate with emerging longevity research

R-Lipoic Acid (R-ALA)

Red Yeast Rice

Red yeast rice is rice fermented with the mold Monascus purpureus. The fermentation produces a family of natural-product polyketides called monacolins, the most clinically relevant of which is monacolin K. Monacolin K is identical in chemical…

Resveratrol

Grape-derived stilbene and sirtuin activator with mixed clinical outcomes

Saw Palmetto

Traditional herbal extract with EMA monograph for prostate and urinary health

Selenium

Essential trace mineral with narrow therapeutic window and anti-cancer implications

Specialized Pro-Resolving Mediators (SPMs)

Specialized pro-resolving mediators (SPMs) are a family of bioactive lipid mediators derived enzymatically from omega-3 fatty acids — primarily EPA and DHA. They include the resolvins (E-series from EPA, D-series from DHA), protectins (from DHA),…

Spermidine

Polyamine autophagy inducer with longevity research implications

Sulforaphane (Broccoli Extract)

Cruciferous phytochemical with potent anti-cancer and detoxification support

TMG/Betaine (Trimethylglycine)

Methyl donor for homocysteine reduction and cellular methylation support

Tongkat Ali (Eurycoma longifolia)

Traditional Southeast Asian herbal root extract for testosterone and vitality support

TUDCA (Tauroursodeoxycholic Acid)

Tauroursodeoxycholic acid (TUDCA) is the taurine-conjugated form of ursodeoxycholic acid (UDCA), a hydrophilic bile acid produced naturally in humans in small quantities. In Europe it has been used clinically since the 1990s for cholestatic liver…

Urolithin A

Postbiotic mitophagy activator for cellular quality control and longevity

Ursolic Acid

Pentacyclic triterpenoid from apple peel with emerging longevity potential

Vitamin B1 (Thiamine / TTFD / Benfotiamine)

Vitamin B2 (Riboflavin)

Vitamin B5 (Pantothenic Acid / Pantethine)

Vitamin B6 (P5P / Pyridoxal-5-Phosphate)

Vitamin K2 (MK-7)

Menaquinone-7 for bone mineralization and vascular health with critical warfarin interactions

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