Supplements
R-Lipoic Acid (R-ALA)
Overview Alpha-lipoic acid exists as two stereoisomers: R-ALA (the biologically native, endogenously produced form) and S-ALA (not found in nature). Most commercial ALA is racemic (R,S). The R-form demonstrates substantially superior bioavailability, tissue uptake, and biological activity …
By Kristopher Crawford
·
08 May 2026
·
1 min read
Overview Alpha-lipoic acid exists as two stereoisomers: R-ALA (the biologically native, endogenously produced form) and S-ALA (not found in nature). Most commercial ALA is racemic (R,S). The R-form demonstrates substantially superior bioavailability, tissue uptake, and biological activity …
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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