Testing & Tracking
DUTCH Urine Hormone Testing
The DUTCH test (Dried Urine Test for Comprehensive Hormones, Precision Analytical) measures a panel of steroid hormones and their metabolites from dried urine spots collected at specified times across a 24-hour period. The test has become a popular…
Hormone Testing Methodology — LC-MS/MS vs Immunoassay
Steroid hormone measurement in blood is dominated by two distinct technologies. Immunoassay — the standard method used by most commercial U.S. clinical laboratories for testosterone, estradiol, cortisol, and most other steroid hormones — uses…
The Comprehensive Thyroid Panel
Thyroid evaluation in U.S. clinical practice traditionally starts with thyroid-stimulating hormone (TSH) — the most sensitive marker of thyroid status in adults with intact hypothalamic-pituitary-thyroid axis function. Free T4, free T3, reverse T3,…
Compounds & Therapies
Anastrozole
Aromatase Inhibitor for Selective Estrogen Reduction
Ashwagandha
A traditional adaptogenic herb with clinical evidence for stress resilience and cognitive function
Boron
An essential trace mineral supporting bone health, hormonal balance, and cognitive function
Cabergoline: A Practical Guide
CJC-1295
Long-Acting GHRH Analog for GH Secretion Research
CJC-1295: A Practical Guide
DHEA (Dehydroepiandrosterone)
The Foundational Prohormone for Hormonal Precursors
DIM (Diindolylmethane)
Cruciferous phytochemical for estrogen metabolism support and hormonal balance
Enclomiphene
The Active Isomer of Clomiphene for Testicular Function Preservation
Estradiol (17β-Estradiol): A Practical Guide
Fadogia Agrestis
A traditional West African plant with limited regulatory guidance and concerning preclinical safety signals requiring clinical oversight
GF9 (Amino Acid Blend)
A proprietary amino acid formulation marketed for growth hormone support with limited independent validation
GHRP-2 (Growth Hormone Releasing Peptide-2): A Practical Guide
GHRP-6: A Practical Guide
Gonadotropin Guide
HCG (Human Chorionic Gonadotropin)
Growth Hormone (Human Growth Hormone, HGH): A Practical Guide
Growth Hormone Secretagogues (Sermorelin, CJC-1295, Ipamorelin, GHRP Class): A Practical Guide
Hexarelin
Hexarelin is a synthetic hexapeptide growth hormone-releasing peptide (GHRP) developed in the early 1990s as part of the GHRP-2/GHRP-6/hexarelin family. At equivalent doses, hexarelin produces growth hormone pulses larger than GHRP-2 or GHRP-6,…
Hormonal Guide
Cabergoline
IGF-LR3 (Insulin-Like Growth Factor-1 Long Arg3)
Potent Modified IGF-1 With Extreme Abuse Potential
Ipamorelin
Selective GH Secretagogue for Research Use
Ipamorelin: A Practical Guide
Kisspeptin
Investigational Reproductive Peptide in Active Research
Levothyroxine (T4)
The Standard Treatment for Thyroid Hormone Replacement
Oxytocin
The Bonding and Trust Hormone for Social and Intimate Function
Pregnenolone
The Original Steroid Hormone Precursor
Progesterone (Micronized): A Practical Guide
Saw Palmetto
Traditional herbal extract with EMA monograph for prostate and urinary health
Selenium
Essential trace mineral with narrow therapeutic window and anti-cancer implications
Sermorelin
FDA-Approved GHRH Analog (Discontinued Commercially, Available via Compounding)
Sermorelin: A Practical Guide
Tadalafil (Cialis)
The Long-Acting Phosphodiesterase-5 Inhibitor for Erectile Function and Hemodynamics
Tesamorelin
FDA-Approved GHRH Analog for HIV-Associated Lipodystrophy
Testosterone
The Gold Standard in Male Hormone Optimization
Thymulin: A Practical Guide
Thyroid T3/Combination (NDT)
Direct T3 or Natural Desiccated Thyroid for Patients Unresponsive to T4 Alone
Tongkat Ali (Eurycoma longifolia)
Traditional Southeast Asian herbal root extract for testosterone and vitality support
Zinc
Essential trace mineral for immune function, protein synthesis, and cellular health
Protocols & Reference
Peptide Stacking Protocol: Research-Based Combination Frameworks
Testosterone Optimization Protocol: A Complete Framework
Protocol Guide Series — Testosterone Optimization Protocol: A Complete Framework
Practices & Lifestyle
Ashwagandha: A Practical Guide
Eleuthero (Siberian Ginseng): A Practical Guide
Fenugreek: A Practical Guide
Holy Basil (Tulsi): A Practical Guide
Iodine: A Practical Guide
Maca (Lepidium meyenii): A Practical Guide
Myo-Inositol: A Practical Guide
Nettle (Urtica dioica): A Practical Guide
Rhodiola Rosea — Adaptogenic Stress and Cognitive Performance
Salidroside: Isolating the Bioactive of Rhodiola
Salidroside is the most-studied bioactive in rhodiola — and, as of 2024, finally available as a fermentation-derived isolated compound. One small Phase II RCT exists; everything else lives in the whole-extract literature. What the data actually say.
Shilajit: A Practical Guide
Tongkat Ali vs Fadogia Agrestis
Tongkat Ali (Eurycoma longifolia) and Fadogia agrestis are the two herbs that have dominated the men's testosterone-supplement conversation since approximately 2020. The pairing was popularized in optimization-medicine influencer content and has…
Tribulus Terrestris: A Practical Guide