Monograph
Growth Hormone Secretagogues (Sermorelin, CJC-1295, Ipamorelin, GHRP Class): A Practical Guide
Overview Growth hormone secretagogues (GHS) are a class of compounds that stimulate endogenous growth hormone release from the anterior pituitary, in contrast to exogenous recombinant hGH (rhGH), which bypasses the pituitary entirely. They act through two distinct receptor pathways: GHRH…
By Kristopher Crawford
·
13 May 2026
·
6 min read
Overview Growth hormone secretagogues (GHS) are a class of compounds that stimulate endogenous growth hormone release from the anterior pituitary, in contrast to exogenous recombinant hGH (rhGH), which bypasses the pituitary entirely. They act through two distinct receptor pathways: GHRH…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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