Overview Estradiol (17β-estradiol, E2) is the primary and most potent endogenous estrogen in humans. It is a steroid hormone synthesized predominantly in the ovaries (in premenopausal women), the testes (in small amounts in men), the adrenal glands, adipose tissue, bone, brain, and vascular…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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