Monograph
SSRIs — Long-Term Use and PSSD
Selective serotonin reuptake inhibitors (SSRIs) — fluoxetine, sertraline, citalopram, escitalopram, paroxetine, fluvoxamine — and the closely related SNRIs (venlafaxine, duloxetine) are among the most-prescribed medication classes in modern…
By Kristopher Crawford
·
30 May 2026
·
5 min read
Selective serotonin reuptake inhibitors (SSRIs) — fluoxetine, sertraline, citalopram, escitalopram, paroxetine, fluvoxamine — and the closely related SNRIs (venlafaxine, duloxetine) are among the most-prescribed medication classes in modern…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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