Compounds & Therapies
Ketamine Therapy
Ketamine is an NMDA-receptor antagonist that has been on the U.S. market as an anesthetic since 1970. In the early 2000s, NIH-funded work demonstrated that sub-anesthetic doses (~0.5 mg/kg IV over 40 minutes) produce rapid and substantial…
Microdosing Psychedelics
Microdosing is the practice of taking sub-perceptual doses of a classical psychedelic — most commonly psilocybin (roughly 0.1–0.5 g of dried Psilocybe cubensis, or about 1–3 mg of pure psilocybin) or LSD (approximately 5–20 mcg) — every few days,…
SSRIs — Long-Term Use and PSSD
Selective serotonin reuptake inhibitors (SSRIs) — fluoxetine, sertraline, citalopram, escitalopram, paroxetine, fluvoxamine — and the closely related SNRIs (venlafaxine, duloxetine) are among the most-prescribed medication classes in modern…