Kristopher Crawford

Mid-Life Cognitive Optimization — A Sober Protocol

Cognitive optimization for men in their 40s-60s pulls from one of the most-marketed and least-evidenced areas in optimization medicine. This protocol layers the actually-evidence-based interventions: foundation (sleep, exercise, hearing, vascular health, sleep apnea), substantial-evidence…

30 May 2026

Recovery and Training Stack — A Performance Optimization Protocol

The recovery stack — creatine, beta-alanine, protein, electrolytes, sleep tools, and the peptide layer — is one of the most-marketed corners of optimization medicine. This protocol distinguishes what actually moves training adaptation and recovery from what's mostly noise. Foundation (sleep…

30 May 2026

Energy and Fatigue — A Diagnostic-First Protocol

Persistent fatigue gets treated as a supplement problem when it's typically a diagnosis problem. This protocol walks the

30 May 2026

Joint and Tendon Optimization — A Layered Protocol

Joint and tendon issues — whether from training, age, or injury — pull from one of the busiest corners of the peptide and supplement market. This protocol layers the evidence: foundation (load management, sleep, protein, mechanical exposure), well-evidenced supplements (collagen with vitamin…

30 May 2026

Anxiety and Mood — A Layered Optimization Protocol

The non-pharmacological and supplement-based options for anxiety and mood often get treated like a single grab-bag. They're not. This protocol layers them by evidence weight: foundation (sleep, exercise, light, breath), well-evidenced botanicals (saffron, ashwagandha, lavender), nutraceutical…

30 May 2026

Erectile Dysfunction — A Stepwise Optimization Protocol

Erectile dysfunction is more often a symptom of underlying physiology than a standalone problem. This protocol walks the evidence-based

30 May 2026

Phentermine/Topiramate (Qsymia) — Second-Line Anti-Obesity in the GLP-1 Era

Qsymia is a fixed-dose combination of immediate-release phentermine (a sympathomimetic appetite suppressant) and extended-release topiramate (an anticonvulsant with appetite-reducing properties through multiple mechanisms), FDA-approved in July 2012…

30 May 2026

Vuity and Pilocarpine Drops for Presbyopia

Presbyopia — the age-related loss of near vision accommodation that affects essentially all adults by their mid-40s — has been managed historically through reading glasses, bifocals, progressive lenses, contact lens monovision, and surgical…

30 May 2026

SSRIs — Long-Term Use and PSSD

Selective serotonin reuptake inhibitors (SSRIs) — fluoxetine, sertraline, citalopram, escitalopram, paroxetine, fluvoxamine — and the closely related SNRIs (venlafaxine, duloxetine) are among the most-prescribed medication classes in modern…

30 May 2026

Pelvic Floor Physical Therapy for Men

Pelvic floor physical therapy (PFPT) for men is one of the most under-prescribed, under-recognized evidence-based interventions in men's health. The male pelvic floor — including the levator ani, coccygeus, and supporting muscle groups — is integral…

30 May 2026

PSA Testing Strategy and Interpretation

Prostate-specific antigen (PSA) testing has been the central screening tool for prostate cancer since the late 1980s. The history of PSA screening is one of the most-debated topics in cancer screening medicine — early enthusiasm produced substantial…

30 May 2026

Microbiome Testing — Viome, ZOE, Sun Genomics

Consumer microbiome testing has emerged as a substantial commercial category over the past decade, with companies including Viome, ZOE, Sun Genomics, Thryve, DayTwo, and various direct-to-consumer offerings sequencing stool samples and returning…

30 May 2026

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