Compounds & Therapies
5-Amino-1MQ — NNMT Inhibitor
5-Amino-1-methylquinolinium iodide (5-amino-1MQ) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide using S-adenosylmethionine (SAM) as a methyl donor. Two metabolic problems flow from…
AOD-9604
Failed Drug Candidate With Misleading GRAS Status
ARA-290 (Cibinetide)
Innate Repair Receptor Agonist in Phase 2 Development
BPC-157
Emerging Peptide for Tissue Repair Research
BPC-157 (Body Protection Compound-157): A Practical Guide
Cartalax — Khavinson Short-Peptide Bioregulator for Cartilage
Cartalax (Ala-Glu-Asp, AED tripeptide) is one of approximately fifteen short-peptide bioregulators developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology beginning in the 1970s. The Khavinson…
Cerebrolysin
Cerebrolysin is a parenteral pharmaceutical preparation of low-molecular-weight peptides and free amino acids derived from enzymatically processed porcine brain tissue. Manufactured by EVER Pharma since the 1970s, it is approved in more than 40…
CJC-1295
Long-Acting GHRH Analog for GH Secretion Research
CJC-1295: A Practical Guide
Dihexa
Angiotensin IV Analog With No Human Safety Data
DSIP — Delta Sleep-Inducing Peptide
Delta sleep-inducing peptide (DSIP) is a small (nine amino acid) neuropeptide first identified in 1977 by Monnier and colleagues in Switzerland, isolated from the cerebral venous blood of rabbits exposed to electrical stimulation that induced…
Epitalon
Unproven Telomerase Activator From Russia
Epitalon (Epithalon): A Practical Guide
Follistatin (FST-344)
Follistatin is a glycoprotein that binds and neutralizes myostatin (GDF-8), activin A, and several bone morphogenetic proteins. Because myostatin is the dominant brake on skeletal-muscle growth, blocking myostatin produces dramatic muscle…
GHK-Cu (Copper Peptide)
Cosmetic Peptide With Topical Benefits and Injectable Research Status
GHK-Cu (Copper Tripeptide): A Practical Guide
GHRP-2 (Growth Hormone Releasing Peptide-2): A Practical Guide
GHRP-6: A Practical Guide
Hexarelin
Hexarelin is a synthetic hexapeptide growth hormone-releasing peptide (GHRP) developed in the early 1990s as part of the GHRP-2/GHRP-6/hexarelin family. At equivalent doses, hexarelin produces growth hormone pulses larger than GHRP-2 or GHRP-6,…
IGF-LR3 (Insulin-Like Growth Factor-1 Long Arg3)
Potent Modified IGF-1 With Extreme Abuse Potential
Ipamorelin
Selective GH Secretagogue for Research Use
Ipamorelin: A Practical Guide
Kisspeptin
Investigational Reproductive Peptide in Active Research
KPV (Lysine-Proline-Valine)
Tripeptide Fragment With Zero Human Evidence
LL-37
Human Cathelicidin Antimicrobial Peptide (Preclinical Only)
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c): A Practical Guide
MOTS-c (Mitochondrial-Derived Peptide)
Preclinical Mitochondrial Peptide With Theoretical Metabolic Benefits
N-Acetyl Semax and N-Acetyl Selank
Semax (a synthetic analog of the N-terminal fragment of ACTH 4-10) and Selank (a synthetic analog of tuftsin) were developed by Russian scientific research institutes beginning in the 1980s-1990s. Both are registered medications in Russia for…
Pinealon
Pinealon (Glu-Asp-Arg) is a synthetic tripeptide developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology. It is part of the broader Khavinson 'short peptide' bioregulator program, which has…
PT-141 (Bremelanotide)
FDA-Approved Melanocortin Agonist (Women Only)
PT-141 (Bremelanotide): A Practical Guide
Selank
Russian-Approved Anxiolytic Peptide (Tuftsin Analog)
Semax
Russian-Approved Neuroprotective Peptide (ACTH Analog)
Sermorelin
FDA-Approved GHRH Analog (Discontinued Commercially, Available via Compounding)
Sermorelin: A Practical Guide
SS-31 (Elamipretide)
Investigational Mitochondrial Protective Peptide in Active Development
TB-500 (Thymosin Beta-4 Fragment): A Practical Guide
TB-500 (Thymosin Beta-4)
Actin-Binding Peptide Under Scrutiny
Tesamorelin
FDA-Approved GHRH Analog for HIV-Associated Lipodystrophy
Thymosin Alpha-1
Approved in 35+ Countries (Except US, EU, UK, Australia, Canada)
Thymosin Beta-4 (Tβ4): A Practical Guide
Thymulin: A Practical Guide
VIP (Vasoactive Intestinal Peptide)
Endogenous Neuropeptide With Limited Clinical Evidence for CIRS