Evidence. Protocol. Truth.

Physician-curated deep dives into the science of men's health optimization.

Tongkat Ali (Eurycoma longifolia)

Traditional Southeast Asian herbal root extract for testosterone and vitality support

13 Apr 2026

TMG/Betaine (Trimethylglycine)

Methyl donor for homocysteine reduction and cellular methylation support

13 Apr 2026

Resveratrol

Grape-derived stilbene and sirtuin activator with mixed clinical outcomes

13 Apr 2026

Pterostilbene β€” The Resveratrol Analog, the LDL Signal, and Why We No Longer Recommend It

Pterostilbene raised LDL cholesterol by 17.1 mg/dL in the best human RCT (Riche 2014, n=80, P=0.001). The sirtuin/longevity claim has not translated to demonstrated human clinical benefit. Vanguard's revised position: we do not recommend oral pterostilbene supplementation.

13 Apr 2026

Neprinol

Proprietary systemic enzyme blend for proteolytic and fibrinolytic support

13 Apr 2026

NAD+ Precursors (NMN/NR)

Cellular energy currency and sirtuin activator with evolving regulatory status

13 Apr 2026

NAC (N-Acetyl Cysteine)

Cellular antioxidant and glutathione precursor for robust defense

13 Apr 2026

Lysine

An essential amino acid supporting collagen synthesis, immune function, and herpes simplex virus management

13 Apr 2026

Leucine

An essential branched-chain amino acid crucial for muscle protein synthesis and metabolic signaling

13 Apr 2026

Inulin

A prebiotic fiber supporting gut microbiota, digestive health, and metabolic markers

13 Apr 2026

HMB (Beta-Hydroxy Beta-Methylbutyrate)

A leucine metabolite supporting muscle protein synthesis and exercise recovery with solid clinical evidence

13 Apr 2026

Fadogia Agrestis

A traditional West African plant with limited regulatory guidance and concerning preclinical safety signals requiring clinical oversight

13 Apr 2026

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