THE VANGUARD BLOG
Physician-curated deep dives into the science of men's health optimization.
Monograph
The short version "Fish oil for your heart" is largely oversold, because the capsule in most cabinets is
30 Jun 2026
Monograph
Glucosamine and chondroitin sulfate are naturally occurring compounds found in healthy cartilage. Glucosamine is an amino sugar used by the body in glycosaminoglycan and proteoglycan synthesis; chondroitin sulfate is a long-chain sulfated…
23 Jun 2026
Monograph
Cartalax (Ala-Glu-Asp, AED tripeptide) is one of approximately fifteen short-peptide bioregulators developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology beginning in the 1970s. The Khavinson…
12 Jun 2026
Protocol
Cognitive optimization for men in their 40s-60s pulls from one of the most-marketed and least-evidenced areas in optimization medicine. This protocol layers the actually-evidence-based interventions: foundation (sleep, exercise, hearing, vascular health, sleep apnea), substantial-evidence…
30 May 2026
Protocol
The recovery stack — creatine, beta-alanine, protein, electrolytes, sleep tools, and the peptide layer — is one of the most-marketed corners of optimization medicine. This protocol distinguishes what actually moves training adaptation and recovery from what's mostly noise. Foundation (sleep…
30 May 2026
Protocol
Persistent fatigue gets treated as a supplement problem when it's typically a diagnosis problem. This protocol walks the
30 May 2026
Protocol
Joint and tendon issues — whether from training, age, or injury — pull from one of the busiest corners of the peptide and supplement market. This protocol layers the evidence: foundation (load management, sleep, protein, mechanical exposure), well-evidenced supplements (collagen with vitamin…
30 May 2026
Protocol
The non-pharmacological and supplement-based options for anxiety and mood often get treated like a single grab-bag. They're not. This protocol layers them by evidence weight: foundation (sleep, exercise, light, breath), well-evidenced botanicals (saffron, ashwagandha, lavender), nutraceutical…
30 May 2026
Protocol
Erectile dysfunction is more often a symptom of underlying physiology than a standalone problem. This protocol walks the evidence-based
30 May 2026
Monograph
Qsymia is a fixed-dose combination of immediate-release phentermine (a sympathomimetic appetite suppressant) and extended-release topiramate (an anticonvulsant with appetite-reducing properties through multiple mechanisms), FDA-approved in July 2012…
30 May 2026
Monograph
Presbyopia — the age-related loss of near vision accommodation that affects essentially all adults by their mid-40s — has been managed historically through reading glasses, bifocals, progressive lenses, contact lens monovision, and surgical…
30 May 2026
Monograph
Selective serotonin reuptake inhibitors (SSRIs) — fluoxetine, sertraline, citalopram, escitalopram, paroxetine, fluvoxamine — and the closely related SNRIs (venlafaxine, duloxetine) are among the most-prescribed medication classes in modern…
30 May 2026
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