Monograph
Mandelic Acid
Mandelic acid is an alpha-hydroxy acid (AHA) derived from bitter almonds. It is structurally similar to glycolic acid and lactic acid but with a substantially larger molecular structure (152.15 g/mol vs glycolic at 76 g/mol). The larger molecule…
By Kristopher Crawford
·
30 May 2026
·
4 min read
Mandelic acid is an alpha-hydroxy acid (AHA) derived from bitter almonds. It is structurally similar to glycolic acid and lactic acid but with a substantially larger molecular structure (152.15 g/mol vs glycolic at 76 g/mol). The larger molecule…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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