Monograph
UDCA (Ursodeoxycholic Acid)
Ursodeoxycholic acid (UDCA, ursodiol) is a hydrophilic, low-toxicity bile acid that occurs naturally as a minor component of human bile (~1-3% of total bile acids) and as a major component of bear bile. Synthetic UDCA was developed in the 1970s and…
By Kristopher Crawford
·
30 May 2026
·
5 min read
Ursodeoxycholic acid (UDCA, ursodiol) is a hydrophilic, low-toxicity bile acid that occurs naturally as a minor component of human bile (~1-3% of total bile acids) and as a major component of bear bile. Synthetic UDCA was developed in the 1970s and…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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