Skincare Guides
Melasma & Hyperpigmentation: A Practical Guide
At a Glance Melasma is a chronic, relapsing hyperpigmentation disorder characterized by symmetric brown-gray patches on sun-exposed areas, predominantly the face. It is driven by the interaction of UV radiation, genetic susceptibility, and hormonal triggers (particularly estrogen and…
By Kristopher Crawford
·
27 April 2026
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6 min read
At a Glance Melasma is a chronic, relapsing hyperpigmentation disorder characterized by symmetric brown-gray patches on sun-exposed areas, predominantly the face. It is driven by the interaction of UV radiation, genetic susceptibility, and hormonal triggers (particularly estrogen and…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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