Monograph
Folate (Methylfolate / Folic Acid): A Practical Guide
Overview Folate is a water-soluble B vitamin (B9) essential for one-carbon metabolism — the biochemical foundation of DNA synthesis, DNA repair, methylation reactions, and amino acid interconversions. The term "folate" covers all biologically active forms; folic acid is the synthetic oxidized…
By Kristopher Crawford
·
13 May 2026
·
3 min read
Overview Folate is a water-soluble B vitamin (B9) essential for one-carbon metabolism — the biochemical foundation of DNA synthesis, DNA repair, methylation reactions, and amino acid interconversions. The term "folate" covers all biologically active forms; folic acid is the synthetic oxidized…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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