Monograph
CLA (Conjugated Linoleic Acid): A Practical Guide
Overview Conjugated linoleic acid (CLA) refers to a family of geometric and positional isomers of linoleic acid (LA, 18:2n-6) in which the double bonds are conjugated (separated by a single bond) rather than methylene-interrupted. The two biologically active isomers are c9,t11-CLA (rumenic…
By Kristopher Crawford
·
13 May 2026
·
3 min read
Overview Conjugated linoleic acid (CLA) refers to a family of geometric and positional isomers of linoleic acid (LA, 18:2n-6) in which the double bonds are conjugated (separated by a single bond) rather than methylene-interrupted. The two biologically active isomers are c9,t11-CLA (rumenic…
In the full monograph
- What it is, and how it works
- What the evidence shows — randomized trials, observational data, animal studies, graded and cited
- Dose, form, and timing
- What to expect, and how soon
- Who should be careful, and what to check first
- The verdict
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